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Cardiovascular mortality associated with low and high temperatures: determinants of inter-region vulnerability in China.

Int J Environ Res Public Health · 2015 · PMC4483679 · PMID 26024362

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an increasing trendno p-value reported
In most regions, an increasing trend in high or low temperature was associated with an increase in cardiovascular mortality, with variation in the magnitude of the temperature effects across regions.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.