Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin.

The functional networks (Figure 2B ) depict the presence of highly significant functional groups known to be involved in many developmental and basic metabolic process like the development of the nervous system, mesenchymal cell, and neuron projections, axon extension, axis elongation, extracellular matrix disassembly and glycosaminoglycan metabolism.

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