The top 10 highly significant hypermethylated loci were protein kinase, cAMP-dependent, regulatory, type I, β ( PRKAR1B ), cannabinoid receptor interacting protein 1 ( C2orf32 ), zinc finger protein 542 ( ZNF542 ), KH domain containing, RNA binding, signal transduction-associated 3 ( KHDRBS ), interferon regulatory factor 4 ( IRF4 ), tissue factor pathway inhibitor 2 ( TFPI2 ), potassium voltage-gated channel, KQT-like subfamily, member 5 ( KCNQ5 ), filamin-binding LIM protein 1 ( FBLIM1 ), eyes absent homolog 4 ( EYA4 ) and spastic paraplegia 20 ( SPG20 ).
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Identification of diagnostic markers in colorectal cancer via integrative epigenomics and genomics data.
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