Keywords macrophage recruitment NG2 proteoglycan pericyte-endothelial cell interaction tumor vascularization tumor microenvironment Tests of life span in tumor-bearing mice reveal that Mac-NG2ko mice exhibit a small trend toward increased survival compared to control mice ( Fig. 1E ).
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NG2 proteoglycan-dependent recruitment of tumor macrophages promotes pericyte-endothelial cell interactions required for brain tumor vascularization.
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