Macroscopic optical physiological parameters correlate with microscopic proliferation and vessel area breast cancer signatures.

Among the available subjects, 15 were Ki67-negative and 3 were Ki67-positive, but a p -value of 0.01 suggests the pilot result may be significant, even with the limited sample size.

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As the tumor grade worsened (i.e., became higher), although a slight trend of increasing rStO 2 and decreasing rHb was observed, it was not statistically significant (n = 29).

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