However we noticed a marginally significant drop in the estimated heritability (to h 2 = 33.9%, se = 6.5%) when all 966,578 SNPs including the 1,000 causal SNPs were used simultaneously in the LMM, indicating that some of the signal from the causal SNPs was being swamped by the remaining SNPs.
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Methodological Considerations in Estimation of Phenotype Heritability Using Genome-Wide SNP Data, Illustrated by an Analysis of the Heritability of Height in a Large Sample of African Ancestry Adults.
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