Analysis of drug combinations: current methodological landscape.

Pharmacol Res Perspect · 2015 · PMC4492765 · PMID 26171228

Europe PMC DOI

hedged sentence

0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

failed to reach significanceP = 0.051so close (0.05 < p ≤ 0.1)

Consider an extreme scenario in which the drug combination barely reaches significance (e.g., P = 0.049) and its individual components narrowly failed to reach significance (e.g., P = 0.051).

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