De novo motif analysis of sequences underlying all 2689 Blimp1 peaks revealed a highly significant consensus DNA binding motif ( Fig 3C ) that closely resembles the canonical Blimp1 binding motif originally identified in SELEX experiments [ 20 ], as well as that identified via ChIP-on-Chip analysis of a human myeloma cell line [ 29 ].
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Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation.
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