a trend towards significancep = 0.061
SN ANOVA test identified significant effects of drug treatment on the levels of p-Akt ( F 3, 21 = 4.243, p = 0.020) and the ratio of p-Akt/Akt ( F 3, 21 = 4.243, p = 0.020) in the SN; ANOVA analysis also indicated a trend towards significance on the levels of p-GSK3β ( F 3, 20 = 2.946, p = 0.061).