highly significantp<0.001
In the RPE cell culture, a similar effect was found with a highly significant decrease in VEGF-A secretion at the apical side at 24 h (0 h: 246.1±75.0 pg/ml, 24h: 90.0±29.6 pg/ml, p<0.001) and at 48 h (48 h: 17.9±8.8 pg/ml, p<0.001; Figure 4C ).