Association Between MTHFR Genetic Variants and Multiple Sclerosis in a Southern Iranian Population.

Int J Mol Cell Med · 2015 · PMC4499570 · PMID 26261797

Europe PMC

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a small trendP= 0.04actually significant

Analysis of the MTHFR A1298C frequency data obtained in this study showed that the heterozygotes ( AC ) were overrepresented in MS patients (67.8% versus 45.7%, P= 0.00) and a small trend for a higher frequency of the homozygous mutant genotype ( CC ) was observed in controls (11.8% versus 2.8%, P= 0.04).

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