Results Aptamers that recognize RNA conformational structures Our in silico analysis of the PCA3 transcript generated a remarkable tertiary structure with a highly significant free energy (ΔG > −975.60 kcal/mol), showing an extensive base pairing within the molecule that led to a very constrained structure with many hairpins and loops ( Fig. 1 ).
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Prostate-specific RNA aptamer: promising nucleic acid antibody-like cancer detection.
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