Barely Significant
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Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.

PLoS One · 2015 · PMC4503404 · PMID 26176234

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a decreasing trendno p-value reported
Other authors have also described a decreasing trend in O-glucuronidation of 4-OH-TAM with increasing numbers of UGT2B7 268Tyr alleles in HLM [ 30 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.