Fleisher et al found a positive trend association between CVLT scores and DMN connectivity z-scores in the precuneus in APOE4 carriers[ 9 ], while anther study reported a negative correlation between DMN synchronization and memory performance[ 10 ]. we found a positive correlation between increased LPHC-vMPFC functional connectivity and baseline MMSE scores in this study, which proved the impact of changed functional connectivity on clinical cognitive manifestations.
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APOE Effects on Default Mode Network in Chinese Cognitive Normal Elderly: Relationship with Clinical Cognitive Performance.
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