Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer.

PLoS One · 2015 · PMC4504492 · PMID 26181325

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borderline significanceno p-value reported

The HER2 + /PIK3CA wt cell line, EFM192A, did show synergy with GSK2141795 and also displayed borderline significance with lapatinib plus GSK690693.

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