Barely Significant
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Randomised, double-blind, placebo-controlled crossover study to investigate different dosing regimens of olodaterol delivered via Respimat® in patients with moderate to severe persistent asthma.

Respir Res · 2015 · PMC4509767 · PMID 26177937

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highly significantno p-value reported
Both total daily doses and all dosing frequencies of olodaterol tested provided highly significant improvements versus placebo in efficacy variables based on pulmonary function tests, albeit with different 24-h bronchodilatory profiles.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.