DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas.

Clin Epigenetics · 2015 · PMC4511034 · PMID 26203307

Europe PMC DOI

hedged sentence

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

borderline significancep = 0.054so close (0.05 < p ≤ 0.1)

carcinomas comparison according to Ogino 5/8 ( p = 0.006) and Weisenberger 3/5 ( p < 0.001) criteria and borderline significance in the adenomas with low-grade dysplasia vs. carcinomas comparison according to Ogino 5/8 ( p = 0.054) criteria.

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