FGF21 deletion exacerbates diabetic cardiomyopathy by aggravating cardiac lipid accumulation.

J Cell Mol Med · 2015 · PMC4511354 · PMID 25823710

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an obvious trendno p-value reported

1C ) was accompanied by an obvious trend of compensative up-regulation of cardiac FGFR1 mRNA levels in WT mice (Fig. 1D ), while the deletion of FGF21 was also accompanied by a slight compensative up-regulation of cardiac FGFR1 mRNA levels under basal conditions, which was significantly amplified under diabetic condition in FGF21KO mice (Fig. 1D ).

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