Barely Significant
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Does pneumococcal vaccination prevent myocardial infarction and stroke in elderly adults?

Open Heart · 2015 · PMC4513539 · PMID 26217544

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However, when the age restriction was not applied (ie, allowing persons younger than 65 years of age to be included), the analysis produced a pooled ratio of 0.86 (95% CI 0.73 to 1.01) and, thus, did not quite reach statistical significance.

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