Applications of magnetic resonance imaging for treatment-resistant late-life depression.

Dialogues Clin Neurosci · 2015 · PMC4518699 · PMID 26246790

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a trend toward significanceno p-value reported

Atrophy of the caudate presented a trend toward significance. 67 In spite of variability within the literature, the most frequently observed regions of atrophy in LLD are the frontal lobe, limbic system, basal ganglia, and thalamus. 68 - 69 Within the frontal lobe, atrophy has been observed in the OFC, 68 , 70 - 74 and the anterior cingulate cortex (ACC).

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