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Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection.

PLoS Pathog · 2015 · PMC4520596 · PMID 26226614

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an increasing trendno p-value reported
In general, there was an increasing trend observed in the IL-6 expression of those responsive DV2-infected wild-type mice from day 1 to day 5 post-infection.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.