Repeated vapor ethanol exposure induces transient histone modifications in the brain that are modified by genotype and brain region.

Front Mol Neurosci · 2015 · PMC4524924 · PMID 26300722

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a nonsignificant trendp = 0.07so close (0.05 < p ≤ 0.1)

Using dot blot, we identified a significant effect of genotype on levels of H3K27me3 [ F (1, 40) = 8.12, p < 0.01] but no effect of EtOH exposure or interaction; post-hoc analysis revealed a nonsignificant trend for decreased levels of H3K27me3 after acute EtOH exposure in α1 SHLA compared to WT littermates ( p = 0.07) (Figure 5A ).

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