The impact of maternal infection with Mycobacterium tuberculosis on the infant response to bacille Calmette-Guérin immunization.

(d) Impact of maternal infection with Mycobacterium tuberculosis on PPD-specific immune responses in infancy Cord blood samples obtained from infants of mothers with LTBI, compared to those without LTBI, showed a weak trend towards higher T-cell responses ( p = 0.48 for IFN-γ ( figure 4 a ), p = 0.20 for IL-2 ( figure 4 b ), p = 0.27 for TNF-α ( figure 4 c ), p = 0.40 for all cytokines, combined ( figure 4 d )).

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