Social exclusion changes histone modifications H3K4me3 and H3K27ac in liver tissue of wild house mice.

For the H3K4me3 mark, the separation at the level of PC1 = 0 was highly significant (p = 7.6x10 -5 , Fig 2A ), but not at lower PCs (see PC1 to PC5 in S3 Fig ).

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When the dataset was divided into two groups at the level of PC1 = 0, this separation was marginally significant (p = 4.8x10 -2 ), but grouping at the level of PC2 = 0 did not give a significant result (p = 9.8x10 -2 ).

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However, Spearman's rank correlation (rho = -0.36) showed marginal significance with a P-value of 0.02 for the H3K27ac dataset.

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