( 24 ) evaluated 13 randomized, controlled trials and reported that the effect of dietary protein restriction (GFR decline in treatment minus control) was greater in patients with than in those without diabetes (5.4 mL/min/year [95% CI 0.3–10.5] to 10.5 mL/min/year, P <0.05), with a nonsignificant trend for a greater effect with each additional year of follow-up.
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