Another result consistent with previous reports is a marginally significant birth ratio biased against the mutant mice in this mixed background (with an average 50% C57BL/6J and 50% 129S1/SvImJ), which implies some variability in the penetrance of the genetic insult, during either pre- or postnatal development.
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Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder.
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