Results of the class level analysis ( Fig 7 ) were in line with the multiple-treatment synthesis of the individual agents and only the group of ADP antagonists achieved a highly significant 25% risk reduction of the composite endpoint (RR: 0.75; 95% CrI: 0.64–0.87, NNT = 87).
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Comparative Efficacy and Safety of Different Antiplatelet Agents for Prevention of Major Cardiovascular Events and Leg Amputations in Patients with Peripheral Arterial Disease: A Systematic Review and Network Meta-Analysis.
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