borderline significantP =0.029
After adjustment for confounders, the association remained significant for patients in the third tHcy quartile and was borderline significant for patients in the fourth quartile compared with patients in the first quartile (adjusted HR, 2.27; 95% CI, 1.06–4.86; P =0.029 and adjusted HR, 2.15; 95% CI, 1.01–4.63; P =0.049, respectively; Table 3 ).