Decline in macrolide resistance rates among Streptococcus pyogenes causing pharyngitis in children isolated in Italy.

Eur J Clin Microbiol Infect Dis · 2015 · PMC4545180 · PMID 26024763

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0.0600

closest p · 1.2× alpha

0.0600

boldest claim

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a decreasing trendp = 0.06so close (0.05 < p ≤ 0.1)

Over the 2-year period under investigation, a decreasing trend of erythromycin resistance was observed (28/293 isolates, 9.6 %, in 2012 vs. 16/299, 5.4 %, in 2013; p = 0.06).

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an increasing trendno p-value reported

In Europe from 2005 onwards, while in some regions macrolide resistance rates continued to remain high with an increasing trend, such as Greece [ 20 ], in others, such as Spain, Portugal, France, and Germany, a significant decrease of macrolide resistance rates was reported [ 14 , 21 – 23 ].

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