Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT.

Nucleic Acids Res · 2015 · PMC4551907 · PMID 25958399

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highly significantno p-value reported

The possibility to reconstitute human telomerase with purified components is highly significant as even the super-telomerase system fail to generate a functional enzyme when hTERT and hTR are produced separately ( 39 ).

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