highly significantP < 1 × 10 −33
Notably, there is highly significant overlap ( P < 1 × 10 −33 ) between the WHSC1 target genes identified and the differentially expressed genes in KMS-11/Cfz (86 out of 887; FC ≥ 1.4) and KMS-34/Cfz (69 out of 888 genes, FC ≥ 1.5).