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Retrospective analyses of optical coherence tomography in recurrent macular edema following intravitreal therapy in patients with retinal vein occlusion.

BMC Ophthalmol · 2015 · PMC4559365 · PMID 26337708

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a decreasing trendno p-value reported
As opposed to a saw-tooth effect of progressively increasing macular thickness, most patients showed either a decreasing trend in macular thickness or a tendency to reach a relatively consistent baseline following each treatment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.