Ipilimumab in the real world: the UK expanded access programme experience in previously treated advanced melanoma patients.

Melanoma Res · 2015 · PMC4560270 · PMID 26225580

Europe PMC DOI

hedged sentences

0.0730

closest p · 1.5× alpha

0.0730

boldest claim

The sentences

a nonsignificant trendP =0.073so close (0.05 < p ≤ 0.1)

On multivariate analysis, statistical significance (at P =0.05) was reached for ECOG PS greater than 0 and low serum albumin level, with a nonsignificant trend for the presence versus the absence of brain metastases ( P =0.073).

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of borderline significanceno p-value reported

However, in our multivariate analysis, in which a total of 109 patients (82 OS events) had complete data for all factors included, both an LDH level greater than two times the ULN and brain metastases were of borderline significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.