borderline significanceP = 0.05516
1a and Table 1 ), and in one out of 532 control samples (c.1642C > T; p.Gln548*, 0.2%), which points towards an enrichment in early-onset CRC cases compared to controls with borderline significance (OR = 8.67; 95% CI, 0.69–455.36; P = 0.05516).