TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse.

EMBO Mol Med · 2015 · PMC4568952 · PMID 26136358

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highly significantno p-value reported

Given that hundreds, if not thousands, of genes specifically regulate fertility, finding a causative mutation frequency of 1% in TEX11 is highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.