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Rheumatic heart disease in Africa: is there a role for genetic studies?

Cardiovasc J Afr · 2015 · PMC4569864 · PMID 25962944

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may be significantno p-value reported
However, of importance for the implementation of control programmes in Africa, it has been suggested that analysis of gene variants of HLA-DRA and the HLA-DRA|HLA-DRB5 inter-region, which may be significant predictors of allergy to penicillin, should occur in African populations. 34 The role of genetic studies ARF and RHD are caused by a combination of immune, environmental and genetic factors.

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