Baseline circulating IL-17 predicts toxicity while TGF-β1 and IL-10 are prognostic of relapse in ipilimumab neoadjuvant therapy of melanoma.

J Immunother Cancer · 2015 · PMC4570556 · PMID 26380086

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a trend towards significancep = 0.06so close (0.05 < p ≤ 0.1)

IL-17 was found to correlate significantly with the incidence of grade 3 diarrhea/colitis when measured at baseline ( p = 0.02) with a trend towards significance at 6 weeks ( p = 0.06).

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