The stabilizing effect at low Gdm-Cl concentration was not significant for hNGF P61S and hNGF P61SR100E, whereas it was highly significant for hNGF R100E ( Fig 3A ).
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Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a "Painless" Lead Investigational Candidate for Therapeutic Applications.
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