THAM reduces CO2-associated increase in pulmonary vascular resistance - an experimental study in lung-injured piglets.

Crit Care · 2015 · PMC4573471 · PMID 26376722

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a decreasing trendno p-value reported

MAP and systemic vascular resistance (SVR) did not differ between the groups at the examined time points, but SVR showed a decreasing trend over time in all three groups.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.