Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment.

32 The difference in mean cIMT between children with FH and unaffected siblings may be significant as early as age 7 years ( Figure 3 A ). 33 Similar findings were observed for mean femoral artery IMT. 34 Coronary calcification is present in ∼25% of 11–23 year olds with phenotypic HeFH, and especially in the aorta in most adolescents with HoFH, although coronary and aortic calcium score is rarel

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