Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity.

J Exp Med · 2015 · PMC4577848 · PMID 26371185

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highly significantno p-value reported

However, we also observed highly significant increases in the level of MHC class II expression on APC populations ( Fig. 8, C, F, and I ), indicating that their overall maturation/activation level is enhanced.

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