Effect of siRNA-Livin on drug resistance to chemotherapy in glioma U251 cells and CD133<sup>+</sup> stem cells.

Exp Ther Med · 2015 · PMC4578066 · PMID 26622485

Europe PMC DOI

hedged sentences

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closest p · 1.0× alpha

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boldest claim

The sentences

an increasing trendP<0.05actually significant

Prior to siRNA-Livin transfection, the expression of MRP1 presented an increasing trend in the U251 cells and U251 stem cells with increasing drug concentrations and intervention times (P<0.05).

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a decreasing trendno p-value reported

Furthermore, following intervention with TMZ, the ACCs and GSCs transfected with siRNA presented a decreasing trend in MRP1 mRNA expression levels with increasing concentrations of TMZ.

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