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Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA.

PLoS One · 2015 · PMC4579133 · PMID 26393516

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an increasing trendno p-value reported
An increasing trend in the prevalence of Cluster 2 sequences and especially this particular haplotype along the years was observed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.