highly significantP < 0.001
A highly significant relationship has been reported between Tc-99m DMSA uptake and cumulative ifosfamide dose ( P < 0.001).[ 26 ] Tc-99m DMSA scintigraphy is a noninvasive and sensitive method for the detection of ifosfamide-induced tubular dysfunction, subclinical injury and to predict risk at retreatment.[ 26 27 28 ] PENTAVALENT DIMERCAPTOSUCCINIC ACID (TC-99M (V) DMSA) The blood pool activity of Tc-99m (V) DMSA is seen up to 3 h and is actively taken up by the growing bones.