Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components.

Mol Cancer · 2015 · PMC4582891 · PMID 26403780

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highly significantno p-value reported

These results suggest that HSP70 plays a highly significant, presumably major key role in SK-TCL-induced DC immunity, and is very effective for suppression of both CD11b + Ly6C + monocytic and CD11b + Ly6G + granulocytic MDSCs activities under in vivo vaccination conditions in mice.

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