Inactivation of the Autolysis-Related Genes lrgB and yycI in Staphylococcus aureus Increases Cell Lysis-Dependent eDNA Release and Enhances Biofilm Development In Vitro and In Vivo.

PLoS One · 2015 · PMC4583396 · PMID 26406329

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extremely significantp < 0.0001actually significant

In parallel, when the promoter was inactive, an extremely significant increase ( p < 0.0001) in the amount of biofilm developed by both the C1HC474 and C2HC474 strains was detected, further confirming the effect of the mutated genes on S . aureus biofilm (Data not shown).

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