Barely Significant
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Trametinib with and without pazopanib has potent preclinical activity in thyroid cancer.

Oncol Rep · 2015 · PMC4583528 · PMID 26324075

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hedged sentence
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closest p · 0.0× alpha
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The sentences

highly significantp<0.0001actually significant
Kaplan-Meier analysis showed highly significant retardation of progression for trametinib or the combination (p<0.0001 vs. vehicle), but not for single agent pazopanib ( Fig. 2C ).

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