Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding.

Front Physiol · 2015 · PMC4584973 · PMID 26441673

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highly significantno p-value reported

These differences were all highly significant and partly persisted after refeeding (+28%, −13%, and +25% for DIO1, DIO2, and DIO3, respectively).

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