Barely Significant
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Evans Syndrome in Children: Long-Term Outcome in a Prospective French National Observational Cohort.

Front Pediatr · 2015 · PMC4586429 · PMID 26484337

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may be significantno p-value reported
Most patients require several second-line treatments whose burden and associated complications may be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.