Association between Helicobacter pylori Infection and Cerebral Small Vessel Disease.

1) Age and hypertension are known to be strong risk factors for small vessel disease, while other risk factors such as coronary artery disease, metabolic syndrome, diabetes, and renal impairment are also likely to be significant, although these findings are not consistent and require further investigation. 2 , 3 , 4) Helicobacter pylori is a gram-negative, spiral bacterium that infects the gastric mucosa and causes various gastrointestinal diseases such as chronic gastritis, peptic ulcers, and gastric cancer. 5) The seropr

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